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Autism Coach

PQQ Mitochondrial Energy Support


PQQ Mitochondrial Energy Support

0.25 LBS
Calculated at checkout

Product Description

PQQ (pyrroloquinoline quinone) is an antioxidant that promotes the creation of new mitochondria, along with supporting heart health and cognitive function. In a recent study, it was shown to protect neurons in the brain against excitoxocity created by having excessive levels of glutamates. Also, in this study, it was shown to work even better when used with CoQ10, which is also part of the ATP energy cycle. Many individuals within the autism spectrum have impaired mitochondrial function as well as excessive levels of glutamates in the brain and insufficient levels of calming neurotransmitters.(1)**
Mitochondria, the power plant inside each cell, provides the energy that fuels cells but also produces toxic by-products as a result energy production. The toxic mitochondrial by-products, reactive oxygen species (ROS), damage the mitochondria and the cell over time and some of this damage is passed along when cells replicate. As a result, cells in older people and those with impaired mitochondrial function are less efficient at creating energy and removing toxins. This leads to lower production of energy and greater build-up of toxins. The number of mitochondria in a cell depend upon how much energy that particular type of cell needs to function (for example there are many mitochondria in cells making up muscles because of the energy exerted by muscles). The number and efficiency of mitochondria function decline as we age or with impaired mitochondrial, which is in large part why older people and those with impaired mitochondrial function have less energy. So low energy is more than a symptom of health issues - it is also a contributor. Supporting mitochondrial function can improve overall health.

Pyrroloquinoline quinone (PQQ) is making waves in some research circles because it appears to provide protection to the brain not only by birthing new mitochondria and making old mitochondria more efficient, but by guarding against other oxidative assaults. A recent study increases this understanding.(1)

Researchers simulated the conditions of stroke by injecting glutamate into rat brain tissue. High levels of ROS were produced as expected leading to widespread neuronal damage. However, in the presence of PQQ much of this damage was avoided.The researchers noted that PQQ did not merely decrease levels of ROS, but also led to the phosphorylation of two kinases, Akt and GSK3. These kinases possess a larger role in neuronal protection and metabolism indicating a more sustained regulatory impact on brain tissue. These observations point to larger signaling functions possessed by PQQ and confirm another mechanism by which PQQ not only protects the brain during trauma but also during normal day-to-day rigors.**

Studies like this one are important because they help researchers and consumers better understand the results of human research. For example, it shines some light on how 20 mg/day PQQ given to aging individuals led to reversals in cognitive decline. Importantly in that study, the effects were increased with co-administration of CoQ10.**

1 Neurochem Res. 2013 Aug;38(8):1661-71.

The recommended dosage of 1 capsule per day provides the following:

* No Daily Value has been established for this ingredient.

Other Ingredients: 
Cellulose, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of gelatin.

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

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