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Autism Coach

Neural Balance - for Natural Calming


Neural Balance - for Natural Calming

0.50 LBS

Product Description

Neural Balance helps with anxiety and anger issues.  When there is an insufficiency of calming neurotransmitters such as GABA and and excess of excitatory neurotransmitters such as glutamate this can result in:

• Lack of focus
• Aggression
• Irregular Sleep patterns
• Social anxiety
• Social withdrawal
• Seizures
• Neurological damage

Neural Balance helps to restore the neurotransmitter balance with reports of:

• Less Aggressive Behavior
• Improved Ability to Focus
• Natural Social Interaction
• Healthier Sleep
• Natural Feeling of Well Being

The primary active ingredient is passionflower extract; it is a tasty powder that can be mixed into water or into a drink blended with other vitamins.  Neural Balance promotes a natural feeling of well-being, calm and focus. 

How It Works

When excitatory neurotransmitters like glutamate make contact with a neuron they cause the neuron to fire and stimulate the next neuron to fire through a synapse.  Too much overfiring by excessive levels of glutamates can lead to behavioral issues, seizures, and neurological damage. 

Recent research has shown that cannabinoid compounds (such as those found in marijuana) also travel through neurons and can cause them to fire BUT after they do so, the cannbinoids travel backwards to the firing neuron inhibit the neuron so it cannot fire again - protecting the neuron from over-firing. Passionflowers also contain the highest GABA content of 21 plants tested and may have other calming components including the bioflavonoid chrysin.(1)

The passionflowers in the blend in Neural Balance naturally contain cannabinoids like marijuana but in a form that does not get you high.  Passionflower cannabinoids are equivalent to the CBD cannabinoid in marijuana that is a non-psychoactive component of marijuana that is used in the autism community for calming and and anti-seizure properties. (THC is the psychoactive cannabinoid in marijuana that is NOT in this product).

Neurons in the brain have cannabinoid receptors which are involved in modulating our perceptions of pain, appetite, mood, memory, motor learning, and the immune system. Cannbinoid receptors are found in the brain, central nervous system and peripheral nervous system

The dendrite (transmission receiving end) of many neurons can produce cannabinoid molecules to inhibit the axon it is receiving transmissions from- so that neuron does not fire as frequently:

Cannbinoid Receptors in Synapse - Edited.jpg

In the diagram above, the neuron on top is transmitting glutamate through one of its axons to a dendrite of another neuron (below). signal the next neuron below through the synapse (gap) between the two neurons. through its dendrite.

Here is anther mechanism by which cannanoid receptors can promote calming neurotransmitters and help to provide excito-toxicity. Endocannabinoid receptor activation can increase the output of GABA, leading to inhibition of excitatory glutamates, reducing levels of anxiety, using a CB1 receptor at the end (terminal) of a of GABA producing neuron:

(A), Under normal condition, the equilibrium between excitatory and inhibitory transmission provides an appropriate emotional reactivity. (B), Stressful experiences leads to an unbalance between excitatory and inhibitory transmission. (C), The overexcitation induced by stressful stimuli triggers CB1 receptor downregulation exclusively on GABAergic terminals, which eventually modifies the balance between GABAergic and glutamatergic CB1 receptor activation by endocannabinoids. (D), This long-lasting CB1 receptor downregulation on GABAergic terminals leads to a persistent increase in the strength of GABAergic inhibition of the glutamatergic transmission.

Scientific Studies on Passion Flower

In the treatment of generalized anxiety disorder passionflower has been found to be as effective as oxazepam (a benzodiazepine). In a groundbreaking study, researchers found that over four weeks both passionflower and oxazepam were equally effective in managing symptoms of anxiety. Passionflower was considered to be superior as a therapy compared to the oxazepam because of a lower incidence of negative side effects, primarily impairment of job performance.(2)

An Australian study found that one cup of passionflower tea nightly significantly improved sleep quality compared to placebo but did not alter sleep latency (time to fall asleep). The authors suggest that the lack of effect may be due to the low dose (one cup vs. the standard dose of 3 cups).(3)

Marijuana addiction may also respond to passionflower. A compound isolated from passionflower, when administered with cannabinoids, prevented the development of tolerance and dependence of marijuana in mice. Administration of the passionflower extract also decreased expression of withdrawal effects associated with the use of marijuana.(4)

Other Ingredients

Magnesium Chloride to quickly restore calm and to prevent inhibited nerve cell communication, which can lead to cell excitability.

CoQ10 to support cellular energy production, immune system support, and for its antioxidant properties.

B6 in the active P5P form for superior absorption without the need for conversion. This offers the full benefit of the active form of B6 immediately upon absorption.B6 is very neuroprotective. 

Digestive Enzymes - a blend to support digestion of foods that are commonly poorly digested in individuals and can also contribute to neurotransmitter imbalance.

Supplement Facts


Other Ingredients

Maltodetrin (tapioca), Citric Acid, Natural Fruit Flavoring, Beet Powder, Stevia (leaf) Extract

No GMOs, gluten, soy, salt, sucrose, corn wheat, casein, potato, rice nuts artificial colors or preservatives.


1. Fisher AA, Purcell P, LeCouteur DG. Toxicity of Passifloraincarnata L. J ToxicolClinToxicol. 2000;38(1):63-6.

2. Dhawan K, Kumar S, Sharma A. Suppression of alcohol-cessation-oriented hyper-anxiety by the benzoflavone moiety of PassifloraincarnataLinneaus in mice. J Ethnopharmacol. 2002;81:239-44.

3. Akhondzadeh S, Kashani L, Mobaseri M, Hosseini SH, Nikzad S, Khani M. Passionflower in the treatment of opiates withdrawal: a double-blind randomized controlled trial. J ClinPharmTher. 2001;26:369-373.
4. Dhawan K. Drug/ substance reversal effects of a novel tri-substituted benzoflavone moiety (BZF) isolated from Passifloraincarnata Linn. – a brief perspective. Addict Biol. 2003;8(4):379-86.



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