Account Navigation

Account Navigation

Currency - All prices are in AUD

Currency - All prices are in AUD
 Loading... Please wait...
Autism Coach

Methylation/Sulfation

What is methylation and why is it important?
 
A Methyl Group is a molecular grouping of atoms, consisting of 1 Carbon Atom and 3 Hydrogen Atoms (expressed in chemistry notation as CH3):
 
methyl-group.jpg
 
Methylation is the biochemical process of transferring a methyl group from a donor molecule (such as trimethylglycine (TMG)) to an acceptor molecule such as homocysteine to convert homocysteine back to methionine.
 
Methylation tends to be impaired in individuals within the autism spectrum, with an estimate by the Pfeiffer Clinic in Chicago of at least 85% of autistic children being classified as under-methylators.  Methylation is required in order to produce glutathione which is an anti-oxidant critical to the body's natural process of detoxification and removal of heavy metals from the body.  Many people within the autism community use TMG, DMG, and methylated, bioavailable B Vitamins to support methylation.  
 
To learn more about methylation, please click here.
 
What is sulfation and why is it important?
 
The use of sulfur bearing molecules in metabolic processes in the body is actually intertwined with methylation in the Methione/Glutathione Transsulfuration Pathway.  This pathway is currently being studied by autism researchers, as it appears to be disrupted for individuals within the autism spectrum. 
 
Individuals within the autism spectrum tend to excrete sulfur. difficulty absorbing and using it and have low levels of sulfur bearing molecules, including the all-important glutathione, which is the key molecule for detoxification and removal of heavy metals from the body.  This pathway is critical to the body's ability to remove toxins through methylation (binding toxins to methyl groups and excreting them from the body). 
 
To learn more about methylation and sulfation and how they work together, please click here.
  • Allithiamine

    Allithiamine $17.00

    Allithiamine (Thiamine tetrahytdrofurfurly disulfide) is is a lipid-soluble form of Vitamin B1. It is typically more easily absorbed and used by children within the autism spectrum than other forms of B1. A sulfur...

  • B-12 Spray

    B-12 Spray $30.00

    Vitamin B12 is a label for a group of compounds known as cobalamins. The most common form of vitamin B12 is called cyanocobalamin.   Cobalamin functions as a source of a methyl group (a carbon molecule) for a very...

  • B-Complex Methylated Vitamin

    B-Complex Methylated Vitamin $16.00

    This supplement contains the full complement of the B-complex vitamins. Vitamins B-1, B-2, and B-6 do not function properly in the body until they are made into their coenzyme forms by the addition of phosphate. Because this...

  • Behavior Balance

    Behavior Balance $28.00

    On back order until the end of May 2015.  However, our state of the art, improved version of Behavior Balance, Behavior Harmony, is  available now!  We have been getting a lot of positive feedback on...

  • Behavior Harmony - B Complex + Methylation Support

    Behavior Harmony Active B Complex Supplement $35.00

    Behavior Harmony is currently out of stock and is estimated to be available in March of 2017.   Years in the planning and formulating, we are  thrilled to introduce Behavior Harmony, a state-of-the-art B...

  • Benfotiamine - Vitamin B1

    Benfotiamine - Vitamin B1 $27.00

    Benfotiamine is a fat-soluble form of thiamine (vitamin B1) with high bioavailability that was developed in Japan in the 1960's. It is especially useful for people needing high levels of thiamine or with impaired absorption...

  • Bioactive Vitamin Mineral Supplement - Powder or Capsule

    Bioactive Vitamin-Mineral Supplement $25.00

    This comprehensive multiple vitamin/mineral supplement contains 28 highly bioavailable essential nutrients in amounts and ratios designed to address nutritional imbalances commonly observed in children with Autism Spectrum...

  • Creatine Powder

    Creatine Powder $14.00

    Creatine Monohydrate is a naturally occurring compound found in the human body. Half of creatine comes from diet, the other half is replenished by body, and typically comes from meat or fish. Creatine helps the body convert...

  • Daily Methyl 1 Cap

    Daily Methyl 1 Cap $25.00

    Daily Methyl 1 Cap s a balanced, convenient, economical one a day multiple vitamin/mineral supplement for elementary age children, teens, and adults. It is gluten, dairy, and citrus free.   Combines 22 nutrients -...

  • DMG Liquid for Methylation Support

    DMG Liquid $34.00

    Dimethylglycine (DMG) provides methyl groups required for detoxification, which are frequently found at insufficient levels for individuals within the autism spectrum. DMG supports immune system, circulatory,...

  • Glutathione Promoter/Homocysteine Calm

    Glutathione Promoter/Homocysteine Calm $12.00

    Homocysteine Calm was originally formulated to lower homocysteine levels which are implicated in heart disease. It also happens to be a complete blend of the vitamins used in a study conducted by Dr. Jill James shown to...

  • Liposomal Glutathione

    Liposomal Glutathione $60.00

    We are extremely pleased to be able to offer this patent-pending, highly absorbable oral form of liquid glutathione. This is the original sodium-benzoate free formulation of lipoceutical glutathione developed by Dr. Tim...

  • Methionine

    Methionine $19.00

    L-Methionine: Is an essential sulfur containing amino acid. Is used to form other amino acids, including S-adenosylmethionine (SAMe), an important methyl donor. and Glutathione, the body's most potent anti-oxidant and the...

  • Methylated B12 and Folate + Intrinsic Factor for Improved Absorption

    Methyl B/12/Folate + Intrinsic Factor $24.00

    This innovative product includes B-12 Intrinsic Factor provides absorbable methylated forms of vitamin B12 and folate plus intrinsic factor, stomach substance, duodenal substance and pancreatic enzyme concentrate to support...

  • Methyl Bs + TMG Capsules

    Methyl Bs + TMG Capsules $27.00

    Methyl Bs + TMG provide four essential B vitamins in their active forms, best utilized by most individuals within the autism spectrum, along with Betaine (Trimethylglycine) to support the methylation cycle. The methylation...

  • Purslane Liquid Concentrate

    Purslane Liquid Concentrate $20.00

    We are pleased to introduce our new super-nutrient Purslane extract, naturally packed with omega 3 oils, Vitamin B12, Glutathione, Melatonin, Vitamin C, Vitamin E, and many minerals including lithium, and neurotransmitters...

  • SAMe Liquid

    SAMe Liquid $37.00

    A critical component of methylation and trans-sulfuration pathways in the body, required for the manufacture of glutathione, the body's most powerful detoxifying molecule. Liquid SAM-e is a stable, liquid form of SAMe...

  • Super Folate/Folinic Acid (5MTHF)

    Super Folate/Folinic Acid (5MTHF) $12.00

    This form of folate, mehtyltetrahydrofolate, is the most bioavailable, containing the methyl donors that help it to be used in the body's metabolic processes. Most individuals within the autism spectrum are deficient in...

  • TMG Crystals

    TMG Crystals $9.00

    Trimethylglycine (TMG), also called anhydrous betaine,is extracted from sugar beets and contains methyl groups (CH3group - 1 Carbon Atom/3 Hydrogen Atoms). Methyl donors are involved in a biochemical process known as...